Note: The health effects are highly dependent on the manner and degree of exposure and on the exact chemical 'species' in which the nickel atoms are present.The allergic effects tend to arise from the Nickel cation Ni ++, but it is not entirely clear which chemical species is reponsible for the carcinogenic effects noted much more commonly in the past. Nickel, which enters the blood stream is Health effects. Workers may be harmed from exposure to nickel. If you've been exposed to large amounts of nickel, and believe it to be affecting your health, it is important to take proper measures to get your body back in balance. Metabolism and Absorption of Nickel When nickel enters the body it is distributed to all organs, but mostly in the kidney, bone, and lungs (Samal and Mishra, 2011). The patient may experience asthma attacks, pulmonary fibrosis , and chronic bronchitis . If nickel enters the body with nickel contaminated air it is retained in the lungs. Exposure to nickel may lead to cancer. Nickel (Ni) is a hard, silvery-white metal that may cause irritation to the skin. Nickel has been found to have some adverse systemic effects on the body. Some of these toxic symptoms include: About 10% of women and 2% of men are highly sensitive to nickel. Preventing nickel levels in the body from getting too low (nickel deficiency). Normally, the immune system defends the body … Chronic noncancer health effects may result from long-term exposure to relatively low concentrations of pollutants. General Nickel Toxicity Information Nickel is a silver-white metal found in the earth’s crust that is used to produce steel, nickel-cadmium batteries, heating fuel, nickel plating and ceramics. Nickel deficiency has not been reported in people, although it may exist, since nickel deficiency has been seen in animals. The level of exposure depends upon the dose, duration, and work being done. Nickel is a common metal that can cause many of these problems. Nickel deficiency can cause diseases such as diabetes, anemia, cirrhosis, uremia, renal failure, abnormal metabolism of liver lipids and phospholipids. The Effects of Nickel on Human Health. Normally, the adult body contains about 10mg of nickel. Exposure can harm the lungs, stomach, and kidneys. Inhalation of nickel also can cause cancer of the lungs, nose and sinuses. Taking trace amounts of nickel in a supplement is effective for preventing nickel deficiency. The aim of this paper is to discuss the sources of Nickel in the body as well as the systemic adverse effects of Nickel as a degradation product of stainless steel surgical implants. Certain amounts of nickel are useful to the human body, but too much nickel can be toxic. Cancer: Prolonged exposure to nickel, when seen as an occupational hazard, my result in cancer of nose and throat. It also contributes to a high amount of oxidative stress. 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